Characteristics of PEGylated Polydiacetylene Liposome and its Inclusion Complex Formation with α-Cyclodextrin
نویسندگان
چکیده
منابع مشابه
Inclusion complex formation of cyclodextrin with its guest and their applications
Cyclodextrin (CD) are cyclic oligosaccharides consisting of glucopyranosyl units linked by α-(1,4) bonds. The widely used natural cyclodextrins are α-, βand γ-cyclodextrin consisting of 6, 7 and 8 glucopyranose units, respectively. The cyclodextrin molecules have a unique structure with a hydrophobic cavity and a hydrophilic surface which can form inclusion complex with a wide variety of guests...
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13C NMR titration studies of inclusion complexes of bicyclic terpenoid, fenchone enantiomers with α-cyclodextrin revealed their 1:2 guest-host stoichiometry. Sequential binding constants were determined indicating a strong binding cooperativity of two α-cyclodextrin to fenchone. The overall association constants were used to calculate the Gibbs free energies of diastereomeric complex formation,...
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One of the methods to enhance bio-accessibility of drugs like Acridone and its oxime is toform inclusion complexes with β-cyclodextrin. The formation of such complexes has beenconfirmed by changes in spectral characteristics and melting point data. The aqueous phasesolubility studies reveal 1:1 stoichiometry between the compound and, β-cyclodextrin. The studyof thermodynamic parameters like ΔG,...
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Cyclodextrins (CDs) can form polypseudorotaxanes (PPRXs) with drugs or drug carriers possessing linear polymers such as polyethylene glycol (PEG). On the other hand, PEGylated liposomes have been utilized as a representative anticancer drug carrier. However, little is known about the formation of CD PPRX with PEGylated liposome. In the present study, we first report the formation of CD PPRX wit...
متن کاملSupramolecular inclusion complex formation and application of b-cyclodextrin with heteroanthracene ring cationic dyes
b-Cyclodextrin forms 1:1 inclusion complexes with methylene blue, azure A, toluidine blue, resorcinol blue, neutral red, safranine T, indigo carmine and acridine orange in aqueous media. The formation constants are determined by differential pulse polarography and spectrophotometry. The supramolecular interaction in the inclusion complexes can be employed to immobilize dyes on an electrode. Thi...
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ژورنال
عنوان ژورنال: Bulletin of the Korean Chemical Society
سال: 2013
ISSN: 0253-2964
DOI: 10.5012/bkcs.2013.34.10.3083